This winter wheat trial at the National Academy of Sciences in Vinnytsia, Ukraine, revealed that Vitazyme, applied at 0.5 liter/ha at the boot stage, produced excellent yield increases of from 7 to 22% for six varieties, whether applied on October 13 or October 18. Extra income ranged from 291 to 1,265 hrn/ha, proving the excellent value of Vitazyme for winter wheat production in Ukraine.