This Ukrainian spring wheat trial proved that Vitazyme on the seeds at planting increased the yield by 10%, whereas an additional 1.0 liter/ha application added 4% more yield. Grain quality was also enhanced with Vitazyme in terms of gluten (+8 to 11%), crude protein (+5 to 9%), grain weight per liter (+1 to 3%), and 1,000 grain weight (+3 to 6%). Stem density, grain number per head, grain weight per head, and disease susceptibility were also increased with Vitazyme.